Easily Access, Analyze, and Manage AlphaFold Structures in PSILO

The web-based macromolecular structural analysis and visualization platform, PSILO, now includes the support of a federated database architecture. This permits the seamless integration of multiple data sources for use within the PSILO platform. The inherent modularity of this infrastructure ensures that in silico models can be readily combined with in-house and public structural data, all of which are indexed and available for exploration and analysis within PSILO. In this webinar, we briefly introduce and review this new federated schema. Using a database of AlphaFold models as an example of a federated input source, we demonstrate how such models are then easily surfaced through executing PSILO queries, are curated and available for pocket similarity searching, and included in the creation of PSILO Project Families.

Airdate: May 5, 2022