Finding Druggable Binding Pockets Using SiteFinder
This video shows how to find druggable binding pockets using the SiteFinder application.
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=80&autoplay=1[label]1:20 Loading a structure directly from the PDB[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=100&autoplay=1[label]1:40 Removing duplicate chains with the Sequence Editor[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=150&autoplay=1[label]2:30 Structure preparation with QuickPrep[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=202&autoplay=1[label]3:22 Annotating the structure by family type[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=264&autoplay=1[label]4:24 Launching SiteFinder[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=268&autoplay=1[label]4:28 Creating Sets[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=387&autoplay=1[label]6:27 Inspecting potential druggable sites[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=470&autoplay=1[label]7:50 Using Alpha Sphere to represent druggable sites[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=490&autoplay=1[label]8:10 Using Dummy Atoms to represent druggable sites[link end]
[link]video.chemcomp[d]com/watch/2VtMGBYvvMkumZqo8A3yJN?second=513&autoplay=1[label]8:33 Identifying residues in druggable sites[link end]
