Fragment-Based Discovery

Fragment Based Drug Design - Scaffold Replacement

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the scaffold replacement operation to replace...
Oct-18-2023

Fragment Based Drug Design - Link Multiple Fragments

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the Link Multiple Fragments to link two separ...
Oct-18-2023

Fragment Based Drug Design - Add Group to Ligand

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the Add Group to ligand operation for growing...
Oct-18-2023

Fragment Based Drug Design - MedChem Transformations

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the MedChem Transformations operation for mak...
Oct-18-2023

Fragment Based Drug Design - Combinatorial Builder

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the Combinatorial Builder for growing a ligan...
Oct-18-2023

Fragment Based Drug Design - Scaffold Replacement; Fused Ring

This video covers the Fragment-Based Drug Design tools in MOE, specifically using the scaffold replacement operation to generat...
Oct-18-2023

Fragment Based Drug Design - Scaffold Replacement; Select R Atoms

This video covers the Fragment Based Drug Design tools in MOE, specifically using the scaffold replacement - Select R atoms ope...
Oct-18-2023

Creating a storyboard and tracking design ideas using Capture

This video covers how to capture the contents of the MOE window (e.g., viewpoints, rendering, surfaces, ligand properties, and ...
Oct-24-2024

CLE: An Interactive Web-Based Combinatorial Library Enumerator

This video covers the Web-Based Combinatorial Library Enumerator in MOE. [link]video.chemcomp[d]com/watch/oamYtMVNqacZ9dnJLB1C...
Oct-18-2023

In Silico Fragment-Based Drug Design: Approaches and Applications

Fragment-based drug design (FBDD) is a key approach in the discovery of high-quality drug candidates. As a complement to biophy...
Nov-21-2023