Fragment Based Drug Design - Scaffold Replacement; Fused Ring
This video covers the Fragment-Based Drug Design tools in MOE, specifically using the scaffold replacement operation to generate a fused ring.
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=30&autoplay=1[label]0:30 Loading a structure[link end]
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=76&autoplay=1[label]1:16 Structure preparation with QuickPrep[link end]
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=196&autoplay=1[label]3:16 Rendering using the System Manager[link end]
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=250&autoplay=1[label]4:10 Setting up the Scaffold Replacement panel[link end]
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=496&autoplay=1[label]8:16 Quantitative analysis using the Database Viewer[link end]
[link]video.chemcomp[d]com/watch/kZhaHoL6CCfAsqmJrL448b?second=552&autoplay=1[label]9:12 Qualitative analysis using the Database Browser[link end]
