Antibody and Biologics Design

Antibody-Antigen Analysis and Mutations

This video covers MOE applications for analyzing an Ab-Ag complex to identify CDR residue mutations that improve solubility, re...
Oct-18-2023

Antibody Modeling and Developability Assessment

This video covers the MOE antibody modeler and how to analyze the resulting models for potential liabilities. [link]video.che...
Oct-18-2023

Virtual Mutagenesis: Protein Builder and Protein Design Applications

This video shows how to perform virtual mutations using the Protein Builder and Protein Design applications. [link]video.chem...
Oct-18-2023

How to Build an Fv model from sequence using the Antibody Modeler

This video shows how to generate a 3D structural model directly from sequence using the MOE Antibody Modeler. [link]video.che...
Oct-18-2023

Analyzing protein surfaces for excess charge or hydrophobicity using Protein Patches

This video shows how to analyze protein surfaces for potential developability issues such as aggregation or solubility. [link...
Oct-18-2023

Finding key contacts for a protein-protein interface using Protein Contacts

This video shows how to analyze key contacts between; a protein–protein interface, for a given loop or region, or a specific re...
Oct-18-2023

New and Enhanced Biologics Features in MOE 2024.06

CCG is pleased to announce the 2024 release of the Molecular Operating Environment, MOE. In this webinar, we will present new f...
Nov-12-2024

Creating a storyboard and tracking design ideas using Capture

This video covers how to capture the contents of the MOE window (e.g., viewpoints, rendering, surfaces, ligand properties, and ...
Oct-24-2024

Building molecules using the Protein Builder

This video shows how to build a peptide from scratch; mutating residues, control backbone geometries, repacking and exploring r...
Feb-01-2024

Preparing a raw PDB file containing a Protein-Protein complex

This video shows how to prepare a raw PDB file containing a Protein-Protein complex (no small molecules present) for use in MOE...
Oct-18-2023