Structural Biology

Performing Solvent Analysis on a Protein-Ligand Complex

This video shows how to use the Solvent Analysis tool, to predict the location and energetic favorability of water molecules in...
Oct-09-2024

X-Ray Crystallography - Structure Preparation, Electron Density and Solvent

The webinar covers methods for evaluating, analyzing, and refining protein models derived from X-ray crystallographic data. Top...
May-03-2024

Using Structures from Cryo Electron Microscopy for Drug Design

Cryo electron microscopy (Cryo EM) allows structures to be solved rapidly for a new biological target. Many drug discovery proj...
Nov-21-2023

🆕 Homology Modeling

This video shows how to generate a 3D structural model directly from sequence using the MOE Homology Modeler. [link]video.chem...
Dec-20-2024

🆕 Sampling and Building Loops with the Loop Modeler

This video shows how to sample and build loop conformations. The Loop and Linker Modeler can be used to sample loops for homol...
Feb-24-2025

Creating a storyboard and tracking design ideas using Capture

This video covers how to capture the contents of the MOE window (e.g., viewpoints, rendering, surfaces, ligand properties, and ...
Oct-24-2024

Solvent Analysis for Lead Optimization

The investigation of water molecule placements, both real and potential, around a protein-ligand complex can provide possible r...
Nov-21-2023

Analyzing protein surfaces for excess charge or hydrophobicity using Protein Patches

This video shows how to analyze protein surfaces for potential developability issues such as aggregation or solubility. [link...
Oct-18-2023

Finding key contacts for a protein-protein interface using Protein Contacts

This video shows how to analyze key contacts between; a protein–protein interface, for a given loop or region, or a specific re...
Oct-18-2023